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Genetic
serious
cat
dog
Polycystic Kidney Disease (PKD)
PKD is a genetic disorder causing fluid-filled cysts to develop in the kidneys, leading to kidney failure over time.
Detailed explanation
Polycystic Kidney Disease (PKD) is an inherited condition characterized by the formation of multiple fluid-filled cysts within the kidneys. These cysts gradually grow, replacing normal kidney tissue and impairing kidney function. While pets are born with these cysts, they are typically small and don't cause problems in early life. Symptoms usually appear later in adulthood as the cysts enlarge and kidney function declines, mirroring those of chronic kidney disease (increased thirst, urination, weight loss, vomiting). PKD is most commonly seen in Persian and related cat breeds, and less frequently in certain dog breeds. Diagnosis is often made via ultrasound. There is no cure, but management focuses on slowing progression and treating symptoms, similar to CKD.
Common symptoms
- Increased thirst
- Increased urination
- Weight loss
- Decreased appetite
- Lethargy
- Vomiting
- Abdominal pain
- Enlarged kidneys (on examination)
Related conditions
Chronic Kidney Disease (CKD)
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